Mon. Jan 18th, 2021

Medical Blog

Validating PSD Method Development

3 min read

When measuring particle size dissolution, it is necessary to check if the method is valid or not.

This is to ensure its strength and integrity. Industries are to check the possible features that can lead to errors and false results.

The software to check the validity of PSD method development should also be valid and updated with recent packages. It should also have words of testimonies of an excellent performance.

The United State  Food and  Drug (UFD) Definition of Validity

Variables Used in Validating PSD Method

You should consider certain factors when ensuring the relevance of any PSD method development. Some are;

1. Sampling

A sample is the representation of a population. Ensure that the sample you want to measure is a correct representative of the whole particles. For instance, some samples will settle at the down part unless you stir them while some will settle on the top of the samples. The disparity in the sample shows that there will be disparity in the use of methods to collect valid result.

2. Stability of Selected Sample in PSD Method

To test if a PSD Method development will result in a robust and specific result, the selected samples are to be tested in different suitable techniques. This will serve as a guide on how to test the dispersion of different particles (such as dry powders, wet powders, emulsions or bigger particles) in different fluid or medium.

3. Attributes of the PSD Techniques

You need to have a vast understanding and  knowledge on the principles that support a method. Such principles include source of errors, degree of automation,  the principle and speed of analysis.



There are some criteria that people consider when testing the validity of the PSD Method development results. Examples are their accuracy, specificity, repeatability, reproductivity, range, linearity, etc.


The soil PSD method development is one of the important physical features of soil.

PSD of soil is known as gradation. It is done by the use of sieving and sedimentation techniques. Agricultural and building industries make use of soil size to classify soils for their various purposes.

Soil Types and PSD Method Development

There are three major categories of soil; clay, silt and sand. They have distinct characteristics and particle sizes. Soil PSD method development helps to distinguish these differences, know the benefits and disadvantages of using each of them. This gives industries insights on the best soil sample to use for their activities.

Uses of Soil Particle Size Distribution


The grain distribution of soil performs various functions to the various industrial sectors;

  • Agriculture: assists in the removal of water from soil surface, which is the drainage system. It also helps in transporting nutrients to all parts of the crops or plants.
  • Civil Engineering: Soil PSD method development helps to design a building site or to know the best land for constructions, such as roads, dams, landfills, leaves. It greatly helps to know the land with most suitable drainage system.
  • Geology and Mining: their ability to know the source or origin of artifacts and mineral resources depends on their knowledge of particle size. It also helps to locate the dispositional environment of geological resources.
  • Laboratories and Accreditation Bodies: Gradation helps in analyzing the best method that gives a robust result that can be used consistently. These data are carried out and documented in the laboratories. Accreditation bodies give license to access the laboratories to make use of such results.

Final say

Soil PSD method development is important in determining the soil water movement (how water moves through a soil), erosion, drainage, aeration, and solute migration.


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